VALIDATION & VERIFICATION OF ANALYTICAL METHODS

USD 15.00 USD 11.25

25% Discount

Mahmoud abdelkhabeer mohamed

Language of video: EN (English)

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This course includes:

03h 05m on-demand videos

6 downloadable resources

Full lifetime access

Certificate of completion

Level:
All
teaching method:
Interactive teaching by writing on board and steps of calculations using camera recording
What are We Going to Teach:
  1. Learn with me how to develop methods for the analysis of the analyte of interest. What are the studies required to develop any method?

  2. Matrix effect study, the chemistry of target analytes, and following steps to get the required method for analytes of interest.

  3. How to select the instrument which is fit for the method.

  4. Learn also how to evaluate most of the performance parameters according to international guidelines to meet the requirements of ISO 17025/2017 edition.

  5. Learn the differences between verification & validation of methods and when you need to verify or validate the method.

  6. Learn also how to ensure the validity of results and to get accurate and reliable results.

  7. Learn how to calculate the limit of detection and the Limit of quantitation in 3 different ways.

  8. Selectivity and specificity for analytes of interest.

  9. Linearity in easy steps (Method linearity).

  10. Learn the differences between Repeatability & reproducibility and how to ensure the repeatability of a specific method to analyze the required analytes.

  11. Accuracy, precision & trueness.

  12. Inter-laboratory comparison.

  13. Intra-laboratory comparison.

  14. Proficiency test (PT) and Certified reference materials (CRM).

  15. Measurement uncertainty calculation for analytical measurement and for sampling, excel sheet attached.

  16. Finally, create your own Excel sheet with a complete example in a very easy procedure.

     

Target Audience:
  • Laboratories analysts, Seniors and juniors
  • Technical managers & Quality managers in labs
  • Calibration laboratories
  • Medical laboratories
  • Academic & research labs
Course objective:
  • To learn how to develop methods for analysis of your analyte of interest based on ISO 17025/2017 requirements
  • To learn how to validate methods using excel sheet in a very easy steps with examples
Course prerequisites:
  • Prepare your own excel sheet, you do not need to have ready made validation excel sheets with a lot of money

Description :

  • This training course is the easiest and most completed material for every analyst who needs to start in laboratory fields and for experience analysts too. not only theoretical but also practical training using excel sheets for calculation where it includes: Full validation example (excel sheet contains validation up to measurement uncertainty calculation for analysis and for sampling in a very easy way), control charts ready to be used for any method (accuracy and precision charts), ANOVA excel sheet ready to be used and also guidelines followed in this course attached with videos. After you will finalize this training and apply every step you will be able o validate or verify any method and that's very important to be accredited according to ISO 17025/2017 edition.

  • Note: All guidelines used are attached.

  1. Learn with me how to develop methods for the analysis of the analyte of interest. What are the studies required to develop any method?

  2. Matrix effect study, the chemistry of target analytes, and following steps to get the required method for analytes of interest.

  3. How to select the instrument which is fit for the method.

  4. Learn also how to evaluate most of the performance parameters according to international guidelines to meet the requirements of ISO 17025/2017 edition.

  5. Learn the differences between verification & validation of methods and when you need to verify or validate the method.

  6. Learn also how to ensure the validity of results and to get accurate and reliable results.

  7. Learn how to calculate the limit of detection and the Limit of quantitation in 3 different ways.

  8. Selectivity and specificity for analytes of interest.

  9. Linearity in easy steps (Method linearity).

  10. Learn the differences between Repeatability & reproducibility and how to ensure the repeatability of a specific method to analyze the required analytes.

  11. Accuracy, precision & trueness.

  12. Inter-laboratory comparison.

  13. Intra-laboratory comparison.

  14. Proficiency test (PT) and Certified reference materials (CRM).

  15. Measurement uncertainty calculation for analytical measurement and for sampling, excel sheet attached.

  16. Finally, create your own Excel sheet with a complete example in a very easy procedure.

     

 

 

 

John Doe

Mahmoud abdelkhabeer mohamed

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Qatar

Mahmoud Abdelkhabeer, Head of veterinary drugs analysis in the central food laboratory in the Ministry of Health,  Doha, Qatar I have been working in the field of laboratories for 18 years till now. During this time I have been involved in the development and validation of many methods such as Aflatoxin in nuts, spices, and cereals using HPLC Agilent, mycotoxins in grains with LC-MS/MS Agilent 6470, and started a new section for analysis of veterinary drugs in food of animal origins such as sulfonamides, tetracyclines, hormones, amphenicol, and quinolones. These methods were developed and validated according to international guidelines and accredited to ISO 17025/2017 edition. I created a youtube channel that includes many lectures in our field and now I am trying to get more audience to my work.

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